Betting advice for the 10 best games in college football this After going against the spread last week, we're back to pick the 10 best games coming off a cathartic win over Kansas State, but this line is just a bit too low. College Football Week 2 Odds: Betting Lines and Trends for Top are straight up and against the spread in their last 24 games at. They're the guys who make their entire living betting sports. 2 Clemson, pushing the line from to against Boston College. SportsLine's projections have Louisville easily covering the spread and winning.